Immunogenicity and tolerogenicity of self-major histocompatibility complex peptides.
نویسندگان
چکیده
منابع مشابه
Immunogenicity and tolerogenicity of self-major histocompatibility complex peptides
Mechanisms involved in self-antigen processing and presentation are crucial in understanding the induction of self-tolerance in the thymus. We examined the immunogenicity of determinants from major histocompatibility complex (MHC) molecules that are expressed in the thymus and have tested peptides derived from the polymorphic regions of class I and class II molecules. We found that two peptides...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1990
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.172.5.1341